For research use only. Not for therapeutic Use.
<p style=/line-height:25px/>Pamabron (Cat.No:I004281) is a common over-the-counter diuretic used for relief of menstrual-associated symptoms. The active diuretic ingredient in pamabrom is 8-bromotheophylline. Pamabrom is available in combination with acetaminophen (paracetamol) for various conditions such as back pain and menstrual relief. The acetaminophen helps reduce menstrual pains and the pamabrom reduces associated bloating.</p>
| Catalog Number | I004281 |
| CAS Number | 606-04-2 |
| Molecular Formula | C11H18BrN5O3 |
| Purity | ≥95% |
| Solubility | 10 mM in DMSO |
| Storage | Store at -20°C |
| Reference | </br>1:Naproxen, paracetamol and pamabrom versus paracetamol, pyrilamine and pamabrom in primary dysmenorrhea: a randomized, double-blind clinical trial. Ortiz MI, Murguía-Cánovas G, Vargas-López LC, Silva R, González-de la Parra M.Medwave. 2016 Oct 24;16(9):e6587. doi: 10.5867/medwave.2016.09.6587. Spanish, English. PMID: 27813503 </br>2:HPTLC and RP-HPLC methods for simultaneous determination of Paracetamol and Pamabrom in presence of their potential impurities. Abdelaleem EA, Naguib IA, Hassan ES, Ali NW.J Pharm Biomed Anal. 2015 Oct 10;114:22-7. doi: 10.1016/j.jpba.2015.04.043. Epub 2015 May 8. PMID: 26001162 </br>3:Development and Validation of Stability-indicating RP-HPLC Method for Estimation of Pamabrom in Tablets. Shah U, Kavad M, Raval M.Indian J Pharm Sci. 2014 May;76(3):198-202. PMID: 25035530 Free PMC Article</br>4:Erythema multiforme secondary to dimenhydrinate in a patient with previous similar reactions to pamabrom. Tan DS, Sklar GE.Ann Pharmacother. 2014 Mar;48(3):425-8. doi: 10.1177/1060028013518728. Epub 2014 Jan 6. PMID: 24396093 </br>5:RP-LC and TLC Densitometric Determination of Paracetamol and Pamabrom in Presence of Hazardous Impurity of Paracetamol and Application to Pharmaceuticals. El-Houssini OM.Anal Chem Insights. 2013 Sep 5;8:73-81. doi: 10.4137/ACI.S12349. eCollection 2013. PMID: 24046511 Free PMC Article</br>6:Fixed drug eruption caused by pamabrom. Min JA, Kim HS, Kim HO, Park YM.Clin Exp Dermatol. 2009 Oct;34(7):e455-6. doi: 10.1111/j.1365-2230.2009.03501.x. Epub 2009 Aug 14. No abstract available. PMID: 19681920 </br>7:Serum sickness-like reaction to Pamabrom. Swanson JK, English JC 3rd.J Drugs Dermatol. 2006 Mar;5(3):284-6. PMID: 16573265 </br>8:Is acetaminophen, and its combination with pamabrom, an effective therapeutic option in primary dysmenorrhoea? Di Girolamo G, Sánchez AJ, De Los Santos AR, González CD.Expert Opin Pharmacother. 2004 Mar;5(3):561-70. Review. PMID: 15013925 </br>9:Fixed drug eruption from pamabrom. Nedorost S, Taylor JS, Camisa C, Tomecki KJ, Helm T, Durkin WJ.Cleve Clin J Med. 1991 Jan-Feb;58(1):33-4. PMID: 1829985 </br>10:A study of diuretic action of pamabrom (2-amino-2-methyl-propanol-1-8-bromotheophylline) in cardiac failure. DOHERTY JE, BEARD OW.Am Heart J. 1953 Aug;46(2):288-90. No abstract available. PMID: 13080166 |
