For research use only. Not for therapeutic Use.
Pangelin is a coumarin that can be found in Ducrosia anethifolia. Pangelin exhibits anti-mycobacterial and anti-tumor activities[1][2].
Pangelin shows a potent cytotoxic activity with the IC50s of 8.6 to 14.6 μg/mL against four kinds of tumor cell lines[1].
| Catalog Number | I044835 |
| CAS Number | 33783-80-1 |
| Synonyms | 4-[(2R)-2-hydroxy-3-methylbut-3-enoxy]furo[3,2-g]chromen-7-one |
| Molecular Formula | C16H14O5 |
| Purity | ≥95% |
| InChI | InChI=1S/C16H14O5/c1-9(2)12(17)8-20-16-10-3-4-15(18)21-14(10)7-13-11(16)5-6-19-13/h3-7,12,17H,1,8H2,2H3/t12-/m0/s1 |
| InChIKey | BVMOMQJYQYBMKL-LBPRGKRZSA-N |
| SMILES | CC(=C)C(COC1=C2C=CC(=O)OC2=CC3=C1C=CO3)O |
| Reference | [1]. Thanh PN, et, al. Cytotoxic coumarins from the root of Angelica dahurica. Arch Pharm Res. 2004 Dec;27(12):1211-5. [2]. Stavr M, et, al. Pangelin, an antimycobacterial coumarin from Ducrosia anethifolia. Planta Med. 2003 Oct;69(10):956-9. |
