Pantoprazole Sodium

For research use only. Not for therapeutic Use.

  • CAT Number: A000088
  • CAS Number: 138786-67-1
  • Molecular Formula: C16H14F2N3NaO4S
  • Molecular Weight: 405.35
  • Purity: ≥95%
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Pantoprazole Sodium is a gastic proton pump inhibitor. It suppresses gastric acid secretion by blocking acid (proton) pump within gastric parietal cells.


Catalog Number A000088
CAS Number 138786-67-1
Synonyms

KF96022 sodium, BY-1023 sodium

Molecular Formula C16H14F2N3NaO4S
Purity ≥95%
Storage Store at -20°C
InChI 1S/C16H14F2N3O4S.Na/c1-23-13-5-6-19-12(14(13)24-2)8-26(22)16-20-10-4-3-9(25-15(17)18)7-11(10)21-16;/h3-7,15H,8H2,1-2H3;/q-1;+1
InChIKey YNWDKZIIWCEDEE-UHFFFAOYSA-N
SMILES COC1=C(C(=NC=C1)CS(=O)C2=NC3=C([N-]2)C=CC(=C3)OC(F)F)OC.[Na+]
Reference

1: Gupta P, Kumar M, Kaushik D. Pantoprazole Sodium Loaded Microballoons for the
Systemic Approach: In Vitro and In Vivo Evaluation. Adv Pharm Bull. 2017
Sep;7(3):461-467. doi: 10.15171/apb.2017.055. Epub 2017 Sep 25. PubMed PMID:
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2: Khashaba PY, Ali HRH, El-Wekil MM. Development of a novel and cost-effective
redox sensor for voltammetric determination of pantoprazole sodium during
pharmacokinetic studies. R Soc Open Sci. 2017 Aug 9;4(8):170324. doi:
10.1098/rsos.170324. eCollection 2017 Aug. PubMed PMID: 28878983; PubMed Central
PMCID: PMC5579098.
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3: Bei C, Libo Z, Hong LI, Guping T, Xiurong HU. [Characterization and stability
of S (-) pantoprazole sodium hydrates]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2017
Mar 25;46(2):160-166. Chinese. PubMed PMID: 28752707.
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4: Jiao H, Li Y, Sun L, Zhang H, Yu L, Yu L, Yuan Z, Xie L, Chen J, Wang Y. A
chiral LC-MS/MS method for the enantioselective determination of R-(+)- and
S-(-)-pantoprazole in human plasma and its application to a pharmacokinetic study
of S-(-)-pantoprazole sodium injection. Biomed Chromatogr. 2017 Oct;31(10). doi:
10.1002/bmc.3980. Epub 2017 May 7. PubMed PMID: 28370240.
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5: Singh DP, Borse SP, Nivsarkar M. Co-administration of quercetin with
pantoprazole sodium prevents NSAID-induced severe gastroenteropathic damage
efficiently: Evidence from a preclinical study in rats. Exp Toxicol Pathol. 2017
Jan;69(1):17-26. doi: 10.1016/j.etp.2016.10.004. Epub 2016 Oct 22. PubMed PMID:
27780667.
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6: Ragab MT, Abd El-Rahman MK, Ramadan NK, El-Ragehy NA, El-Zeany BA. Novel
potentiometric application for the determination of pantoprazole sodium and
itopride hydrochloride in their pure and combined dosage form. Talanta. 2015 Jun
1;138:28-35. doi: 10.1016/j.talanta.2015.01.045. Epub 2015 Feb 9. PubMed PMID:
25863367.
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7: Ramadan NK, El-Ragehy NA, Ragab MT, El-Zeany BA. Simultaneous determination of
a binary mixture of pantoprazole sodium and itopride hydrochloride by four
spectrophotometric methods. Spectrochim Acta A Mol Biomol Spectrosc. 2015 Feb
25;137:463-70. doi: 10.1016/j.saa.2014.09.003. Epub 2014 Sep 10. PubMed PMID:
25238185.
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8: Naharcy MI, Cintosun U, Ozturk A, Bozoglu E, Doruk H. Pantoprazole
sodium-induced hyponatremia in a frail elderly adult. J Am Geriatr Soc. 2014
Apr;62(4):787-8. doi: 10.1111/jgs.12767. PubMed PMID: 24731036.
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9: Bhatt NM, Chavada VD, Sanyal M, Shrivastav PS. Manipulating ratio spectra for
the spectrophotometric analysis of diclofenac sodium and pantoprazole sodium in
laboratory mixtures and tablet formulation. ScientificWorldJournal. 2014 Feb
18;2014:495739. doi: 10.1155/2014/495739. eCollection 2014. PubMed PMID:
24701171; PubMed Central PMCID: PMC3948650.
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10: Biju PG, Gubrij I, Garg S, Gupta PK, Hauer-Jensen M, Burnett AF. Radiation
lethality potentiation in total body irradiated mice by a commonly prescribed
proton pump inhibitor, Pantoprazole sodium. Int J Radiat Biol. 2014
Jul;90(7):554-9. doi: 10.3109/09553002.2014.905727. PubMed PMID: 24646079; PubMed
Central PMCID: PMC4378842.

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