For research use only. Not for therapeutic Use.
LY-165,163 is a selective 5-HT1A and 5-HT1D serotonin receptor antagonists.
| Catalog Number | M120055 |
| CAS Number | 1814-64-8 |
| Molecular Formula | C19H22F3N3 |
| Purity | ≥95% |
| Target | 5-HT1A/5-HT1D serotonin Receptor Antagonist |
| Storage | -20°C |
| IUPAC Name | 4-[2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethyl]aniline |
| InChI | InChI=1S/C19H22F3N3/c20-19(21,22)16-2-1-3-18(14-16)25-12-10-24(11-13-25)9-8-15-4-6-17(23)7-5-15/h1-7,14H,8-13,23H2 |
| InChIKey | GAAKALASJNGQKD-UHFFFAOYSA-N |
| SMILES | C1CN(CCN1CCC2=CC=C(C=C2)N)C3=CC=CC(=C3)C(F)(F)F |
| Reference | </br>1:Association of maternal serum PAPP-A levels, nuchal translucency and crown rump length in first trimester with adverse pregnancy outcomes: Retrospective cohort study. Bilagi A, Burke DL, Riley RD, Mills I, Kilby MD, Morris RK.Prenat Diagn. 2017 May 17. doi: 10.1002/pd.5069. [Epub ahead of print] PMID: 28514830 </br>2:Nuchal translucency measurement, free β-hCG and PAPP-A concentrations in IVF/ICSI pregnancies: systematic review and meta-analysis. Cavoretto P, Giorgione V, Cipriani S, Viganò P, Candiani M, Inversetti A, Ricci E, Parazzini F.Prenat Diagn. 2017 Apr 17. doi: 10.1002/pd.5052. [Epub ahead of print] Review. PMID: 28419502 </br>3:Preanalytical stability of maternal serum markers hCGβ and PAPP-A. Veyrat B, Tosetti F, Morin JF, Moineau MP, Piedimonte A, Clément P, Dreux S, Muller F.Ann Biol Clin (Paris). 2017 Apr 1;75(2):158-166. doi: 10.1684/abc.2017.1230. PMID: 28377328 </br>4:The longevity of para-aminopropiophenone (PAPP) wild dog baits and the implications for effective and safe baiting campaigns. Gentle M, Speed J, Allen BL, Harris S, Haapakoski H, Bell K.Environ Sci Pollut Res Int. 2017 May;24(13):12338-12346. doi: 10.1007/s11356-017-8668-3. Epub 2017 Mar 29. PMID: 28357798 </br>5:Surgically Induced Necrotizing Scleritis Following Strabismus Surgery Treated Successfully with Topical N-acetylcysteine in a Child with Congenital Fibrosis of Extraocular Muscles and Varadi Papp Syndrome. Rajamani M, Nagasubramanian V, Ayyavoo A, Raghupathy P, Dandapani R.Strabismus. 2017 Mar;25(1):39-42. doi: 10.1080/09273972.2016.1277768. Epub 2017 Jan 31. PMID: 28140732 </br>6:PAPP-A: a promising therapeutic target for healthy longevity. Conover CA, Oxvig C.Aging Cell. 2017 Apr;16(2):205-209. doi: 10.1111/acel.12564. Epub 2016 Dec 29. Review. PMID: 28035757 Free PMC Article</br>7:Association of serum PAPP-A levels in first trimester with small for gestational age and adverse pregnancy outcomes: systematic review and meta-analysis. Morris RK, Bilagi A, Devani P, Kilby MD.Prenat Diagn. 2017 Mar;37(3):253-265. doi: 10.1002/pd.5001. Epub 2017 Feb 17. PMID: 28012202 </br>8:Crown-rump length audit plots with the use of operator-specific PAPP-A and β-hCG median MoM. Sabria J, Guirado L, Miró I, Gómez-Roig MD, Borrell A.Prenat Diagn. 2017 Mar;37(3):229-234. doi: 10.1002/pd.4996. Epub 2017 Jan 25. PMID: 28006080 </br>9:The utility of first trimester uterine artery Doppler, placental volume and PAPP-A levels alone and in combination to predict preeclampsia. Yücel B, Gedikbasi A, Dündar O, Olgac Y, Yıldırım D, Yıldırım G, Polat I.Pregnancy Hypertens. 2016 Oct;6(4):269-273. doi: 10.1016/j.preghy.2016.04.007. Epub 2016 May 3. PMID: 27939466 </br>10:Lower placental growth factor and higher free β-hCG and PAPP-A levels in the fetal circulation of near-term pregnancies complicated with severe preeclampsia. Paredes V, Espinoza-Caicedo JA, Salazar-Pousada D, Escobar GS, Pérez-López FR, Chedraui P.Gynecol Endocrinol. 2017 Jan;33(1):79-81. doi: 10.1080/09513590.2016.1241228. Epub 2016 Nov 4. PMID: 27809614 |
