For research use only. Not for therapeutic Use.
PAR-4 (1-6) amide human is an N-terminal fragment of protease-activated receptor 4 (PAR4). PAR-4 (1-6) amide human induce platelet aggregation[1].
PAR-4 (1-6) amide human (50, 100 µM) induces platelet aggregation[1].
| Catalog Number | I042258 |
| CAS Number | 245443-51-0 |
| Synonyms | (2S)-2-[[2-[[(2S)-1-[(2S)-2-[(2-aminoacetyl)amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-N-[(2S)-1-amino-3-methyl-1-oxobutan-2-yl]pentanediamide |
| Molecular Formula | C28H42N8O8 |
| Purity | ≥95% |
| InChI | InChI=1S/C28H42N8O8/c1-15(2)24(25(31)41)35-26(42)18(9-10-21(30)38)33-23(40)14-32-27(43)20-4-3-11-36(20)28(44)19(34-22(39)13-29)12-16-5-7-17(37)8-6-16/h5-8,15,18-20,24,37H,3-4,9-14,29H2,1-2H3,(H2,30,38)(H2,31,41)(H,32,43)(H,33,40)(H,34,39)(H,35,42)/t18-,19-,20-,24-/m0/s1 |
| InChIKey | NIUWXNGGQOLCDN-XHOYROJHSA-N |
| SMILES | CC(C)C(C(=O)N)NC(=O)C(CCC(=O)N)NC(=O)CNC(=O)C1CCCN1C(=O)C(CC2=CC=C(C=C2)O)NC(=O)CN |
| Reference | [1]. Shimizu M, et al. Thrombin-induced platelet aggregation -effect of dabigatran using automated platelet aggregometry. Platelets. 2020;31(3):360-364. |
