For research use only. Not for therapeutic Use.
Paramethasone Acetate is a fluorinated glucocorticoid with anti-inflammatory and immunosuppressant properties.
| Catalog Number | R018488 |
| CAS Number | 1597-82-6 |
| Synonyms | (6α,11β,16α)-21-(Acetyloxy)-6-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione; 16α-Methyl-6α-fluoroprednisolone 21-acetate; 21-Acetyl-6α-fluoro-16α-methylprednisolone; 6α-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 2 |
| Molecular Formula | C24H31FO6 |
| Purity | ≥95% |
| Storage | Store at -20°C |
| IUPAC Name | [2-[(6S,8S,9S,10R,11S,13S,14S,16R,17R)-6-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate |
| InChI | InChI=1S/C24H31FO6/c1-12-7-16-15-9-18(25)17-8-14(27)5-6-22(17,3)21(15)19(28)10-23(16,4)24(12,30)20(29)11-31-13(2)26/h5-6,8,12,15-16,18-19,21,28,30H,7,9-11H2,1-4H3/t12-,15+,16+,18+,19+,21-,22+,23+,24+/m1/s1 |
| InChIKey | HYRKAAMZBDSJFJ-LFDBJOOHSA-N |
| SMILES | CC1CC2C3CC(C4=CC(=O)C=CC4(C3C(CC2(C1(C(=O)COC(=O)C)O)C)O)C)F |
| Reference | </br>1:Delayed local allergic reaction to intralesional paramethasone acetate. Miranda-Romero A, Bajo-del Pozo C, Sánchez-Sambucety P, Martinez-Fernandez M, Garcia-Muñoz M.Contact Dermatitis. 1998 Jul;39(1):31-2. No abstract available. PMID: 9686977 </br>2:Paramethasone acetate (PA): corticosteroid potency vs hypothalamic pituitary-gonadal axis. Cortés-Gallegos V, Alonso R, Castañeda G, Sojo I, Carranco A, Cervantes C, Parra A.J Steroid Biochem. 1984 Jan;20(1):353-6. PMID: 6423900 </br>3:Effect of paramethasone acetate upon estrogen action. Cortés-Gallegos V, Carranco A, Sojo I, Alonso R, Valenzuela-Duriet P.Fertil Steril. 1982 Mar;37(3):402-5. PMID: 7060790 </br>4:[Efficacy of an injectable preparation of paramethasone acetate and phosphate in seasonal allergic rhinitis]. Fuentes, Vigaray.Allergol Immunopathol (Madr). 1981 Mar-Apr;9(2):153-4. Spanish. No abstract available. PMID: 7293877 </br>5:Effect of paramethasone acetate on women with secondary amenorrhea: a preliminary report. Cortés-Gallegos V, Alonso-Uriarte ME, Said LE, Cervantes C, Parra A.Fertil Steril. 1978 Apr;29(4):402-6. PMID: 77230 </br>6:[Treatment of sport injuries by using paramethasone acetate]. Montes Eeyes JS.Rev Esp Reum Enferm Osteoartic. 1976;19(2):203-24. Spanish. No abstract available. PMID: 959639 </br>7:Effect of paramethasone acetate on ovarian steroids and gonadotropins. I. Normal menstrual cycle. Cortés-Gallegos V, Gallegos AJ, Tovar NB, Cervantes C, Parra A.J Clin Endocrinol Metab. 1975 Aug;41(2):215-20. PMID: 1159039 </br>8:[Clinical study of injectable paramethasone acetate: comparative study on the therapeutic effect of 6-alpha-fluoro-16-alpha-methyl-prednisolone-21-acetate administered orally and parenterally]. Menarini C, Lanzarini AM.Clin Ter. 1971 Dec 31;59(6):499-505. Italian. No abstract available. PMID: 5143383 </br>9:[Results obtained in the treatment of alopecia areata with local infiltrations of paramethasone acetate]. Payá Díaz F.Actas Dermosifiliogr. 1971 Jul-Aug;62(7):283-6. Spanish. No abstract available. PMID: 5163454 </br>10:[Injectable paramethasone acetate in surgical practice]. Desbrosses J.Lyon Med. 1970 Nov 29;224(39):741-3. French. No abstract available. PMID: 5485437 |
