For research use only. Not for therapeutic Use.
Parecoxib (CAT: I002517) is a potent and selective inhibitor of cyclooxygenase-2 (COX-2), an enzyme involved in the synthesis of prostaglandins. By specifically targeting COX-2, parecoxib suppresses the production of prostaglandins, which are associated with inflammation, pain, and fever. Parecoxib’s selective inhibition of COX-2 offers a potential advantage over non-selective NSAIDs by reducing the risk of gastrointestinal complications. It is commonly used as an analgesic and anti-inflammatory agent in the management of acute pain, including postoperative pain, making it a valuable option for pain relief in various clinical settings.
| Catalog Number | I002517 |
| CAS Number | 198470-84-7 |
| Synonyms | N-[4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)phenyl]sulfonylpropanamide |
| Molecular Formula | C19H18N2O4S |
| Purity | ≥95% |
| Target | COX |
| Solubility | 10 mM in DMSO |
| Storage | Store at -20C |
| IUPAC Name | N-[4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)phenyl]sulfonylpropanamide |
| InChI | 1S/C19H18N2O4S/c1-3-17(22)21-26(23,24)16-11-9-14(10-12-16)18-13(2)25-20-19(18)15-7-5-4-6-8-15/h4-12H,3H2,1-2H3,(H,21,22) |
| InChIKey | TZRHLKRLEZJVIJ-UHFFFAOYSA-N |
| SMILES | CCC(=O)NS(=O)(=O)C1=CC=C(C=C1)C2=C(ON=C2C3=CC=CC=C3)C |
