Paromomycin

• CAT Number: I034238
• CAS Number: 7542-37-2
• Molecular Formula: C23H45N5O14
• Molecular Weight: 615.63
• Purity: 98%
• Synonyms: Paromomycin; R 400; R-400; R400; Crestomycin
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: (2S,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-(((2R,3S,4R,5S)-5-(((1R,2R,3S,5R,6S)-3,5-diamino-2-(((2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-6-hydroxycyclohexyl)oxy)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl)oxy)tetrahydro-2H-pyran-3,4-diol
• InChI: InChI=1S/C23H45N5O14/c24-2-7-13(32)15(34)10(27)21(37-7)41-19-9(4-30)39-23(17(19)36)42-20-12(31)5(25)1-6(26)18(20)40-22-11(28)16(35)14(33)8(3-29)38-22/h5-23,29-36H,1-4,24-28H2/t5-,6+,7+,8-,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+/m1/s1
• InChIKey: UOZODPSAJZTQNH-LSWIJEOBSA-N
• SMILES: NC[C@@H]1O[C@@H]([C@@H]([C@H]([C@@H]1O)O)N)O[C@H]2[C@H]([C@@H](O[C@@H]2CO)O[C@@H]3[C@H]([C@@H](C[C@@H]([C@H]3O[C@H]4O[C@@H]([C@H]([C@@H]([C@H]4N)O)O)CO)N)N)O)O

Paromomycin (Cat.No:I034238) is an aminoglycoside antibiotic used to treat various types of infections, particularly those caused by certain parasites and bacteria. It is effective against intestinal parasites like Entamoeba histolytica and Giardia lamblia. Paromomycin works by inhibiting protein synthesis in the microorganisms, leading to their elimination.

Reference

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