For research use only. Not for therapeutic Use.
Parsaclisib (Cat.No:I011978) is a potent and selective inhibitor of phosphatidylinositol 3-kinase (PI3K) delta, a key enzyme involved in cell signaling pathways. It is being investigated as a potential treatment for hematological malignancies, including B-cell malignancies. Parsaclisib has shown promising results in clinical trials, demonstrating its potential as a targeted therapy for these diseases.
| Catalog Number | I011978 |
| CAS Number | 1426698-88-5 |
| Synonyms | Parsaclisib;(4R)-4-{3-[(1S)-1-(4-amino-3-methyl-1H-pyrazolo[3,4- d]pyrimidin-1-yl)ethyl]-5-chloro-2-ethoxy- 6-fluorophenyl}pyrrolidin-2-one |
| Molecular Formula | C20H22ClFN6O2 |
| Purity | ≥95% |
| Target | PI3K |
| Solubility | Soluble in DMSO |
| Storage | Store at 0-8 °C |
| IUPAC Name | (4R)-4-[3-[(1S)-1-(4-amino-3-methylpyrazolo[3,4-d]pyrimidin-1-yl)ethyl]-5-chloro-2-ethoxy-6-fluorophenyl]pyrrolidin-2-one |
| InChI | InChI=1S/C20H22ClFN6O2/c1-4-30-18-12(6-13(21)17(22)16(18)11-5-14(29)24-7-11)10(3)28-20-15(9(2)27-28)19(23)25-8-26-20/h6,8,10-11H,4-5,7H2,1-3H3,(H,24,29)(H2,23,25,26)/t10-,11-/m0/s1 |
| InChIKey | ZQPDJCIXJHUERQ-QWRGUYRKSA-N |
| SMILES | CCOC1=C(C(=C(C=C1C(C)N2C3=C(C(=N2)C)C(=NC=N3)N)Cl)F)C4CC(=O)NC4 |
