For research use only. Not for therapeutic Use.
Pascolizumab (SB-240683) is a humanized anti-IL-4 monoclonal antibody. Pascolizumab has the potential for the research of asthma[1].
Pascolizumab binding of IL-4 inhibits IL-4 interaction with the alpha chain of the IL-4 receptor[1].
Pascolizumab (0-10000 pM; 3 days) shows anti-proliferative activity with IC50 values of 157, 377 pM for T-cell and Tonsil B-cell, respectively[1].
| Catalog Number | I042085 |
| CAS Number | 331243-22-2 |
| Purity | ≥95% |
| Reference | [1]. Hart TK, et al. Preclinical efficacy and safety of pascolizumab (SB 240683): a humanized anti-interleukin-4 antibody with therapeutic potential in asthma. Clin Exp Immunol. 2002 Oct;130(1):93-100. |
