For research use only. Not for therapeutic Use.
PBR28 is an TSPO modulator, which can be used for prevention research of Pulmonary Arterial Hypertension (PAH). PBR28 can be used to trace 18 KDa transporter (TSPO) by adding radioactive labeling, which plays an important role in brain positron emission tomography (PET) imaging studies[1].
| Catalog Number | I041170 |
| CAS Number | 253307-65-2 |
| Synonyms | N-[(2-methoxyphenyl)methyl]-N-(4-phenoxypyridin-3-yl)acetamide |
| Molecular Formula | C21H20N2O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C21H20N2O3/c1-16(24)23(15-17-8-6-7-11-20(17)25-2)19-14-22-13-12-21(19)26-18-9-4-3-5-10-18/h3-14H,15H2,1-2H3 |
| InChIKey | DHZBNHMEIOBPAE-UHFFFAOYSA-N |
| SMILES | CC(=O)N(CC1=CC=CC=C1OC)C2=C(C=CN=C2)OC3=CC=CC=C3 |
| Reference | [1]. Sander CY, et al. [11C]PBR28 radiotracer kinetics are not driven by alterations in cerebral blood flow. J Cereb Blood Flow Metab. 2021 Nov;41(11):3069-3084. |
