For research use only. Not for therapeutic Use.
PCAF-IN-1 is a highly selective PCAF inhibitor. PCAF-IN-1 is a antitumor agents, which can be used in tumor research research[1].
PCAF-IN-1 (Compound 32) (10 μM, 72 hours; human tumor cell lines) exerts the most potent antitumor activities against human cancer cell lines[1].
| Catalog Number | I043500 |
| CAS Number | 2439194-86-0 |
| Synonyms | [3-(4-chlorophenyl)-[1,2,4]triazolo[3,4-a]phthalazin-6-yl]hydrazine |
| Molecular Formula | C15H11ClN6 |
| Purity | ≥95% |
| InChI | InChI=1S/C15H11ClN6/c16-10-7-5-9(6-8-10)14-19-20-15-12-4-2-1-3-11(12)13(18-17)21-22(14)15/h1-8H,17H2,(H,18,21) |
| InChIKey | DXGDDBPXRDYXCP-UHFFFAOYSA-N |
| SMILES | C1=CC=C2C(=C1)C(=NN3C2=NN=C3C4=CC=C(C=C4)Cl)NN |
| Reference | [1]. Turky A, et al. Design, synthesis, and antitumor activity of novel compounds based on 1,2,4-triazolophthalazine scaffold: Apoptosis-inductive and PCAF-inhibitory effects. Bioorg Chem. 2020 Aug;101:104019. |
