PCAF-IN-1

• CAT Number: I043500
• CAS Number: 2439194-86-0
• Molecular Formula: C15H11ClN6
• Molecular Weight: 310.74
• Purity: ≥95%
• Synonyms: [3-(4-chlorophenyl)-[1,2,4]triazolo[3,4-a]phthalazin-6-yl]hydrazine
• InChI: InChI=1S/C15H11ClN6/c16-10-7-5-9(6-8-10)14-19-20-15-12-4-2-1-3-11(12)13(18-17)21-22(14)15/h1-8H,17H2,(H,18,21)
• InChIKey: DXGDDBPXRDYXCP-UHFFFAOYSA-N
• SMILES: C1=CC=C2C(=C1)C(=NN3C2=NN=C3C4=CC=C(C=C4)Cl)NN

PCAF-IN-1（Cat No.:I043500）is a selective inhibitor of p300/CBP-associated factor (PCAF), a histone acetyltransferase that plays a key role in regulating gene expression through chromatin modification. PCAF is involved in various cellular processes, including transcription, cell cycle progression, and apoptosis. By inhibiting PCAF, PCAF-IN-1 can influence the acetylation of histones and non-histone proteins, potentially affecting gene expression and cellular function. This compound is being studied for its therapeutic potential in cancer, inflammation, and other diseases where PCAF activity contributes to abnormal gene regulation and disease progression.