For research use only. Not for therapeutic Use.
PCSK9-IN-11（Cat No.:I042354）is a small molecule inhibitor designed to target proprotein convertase subtilisin/kexin type 9 (PCSK9), a protein that regulates cholesterol levels by promoting the degradation of LDL receptors. By inhibiting PCSK9, this compound aims to increase LDL receptor activity, leading to lower levels of low-density lipoprotein (LDL) cholesterol in the bloodstream. PCSK9-IN-11 holds potential therapeutic applications in treating hypercholesterolemia and cardiovascular diseases. Ongoing research explores its efficacy in managing high cholesterol levels and preventing atherosclerosis, providing a novel approach to lipid regulation and heart disease prevention.
| CAS Number | 2882035-56-3 |
| Synonyms | 7-[(3-chloro-2-fluorophenyl)methyl]-8-(2-hydroxyethylamino)-1,3-dimethylpurine-2,6-dione |
| Molecular Formula | C16H17ClFN5O3 |
| Purity | ≥95% |
| IUPAC Name | 7-[(3-chloro-2-fluorophenyl)methyl]-8-(2-hydroxyethylamino)-1,3-dimethylpurine-2,6-dione |
| InChI | InChI=1S/C16H17ClFN5O3/c1-21-13-12(14(25)22(2)16(21)26)23(15(20-13)19-6-7-24)8-9-4-3-5-10(17)11(9)18/h3-5,24H,6-8H2,1-2H3,(H,19,20) |
| InChIKey | UVWKWCCDYSHPMZ-UHFFFAOYSA-N |
| SMILES | CN1C2=C(C(=O)N(C1=O)C)N(C(=N2)NCCO)CC3=C(C(=CC=C3)Cl)F |
