For research use only. Not for therapeutic Use.
PCSK9 Protein, Mouse (HEK293, His)（Cat No.:I042691）is a recombinant proprotein convertase subtilisin/kexin type 9 (PCSK9) expressed in HEK293 cells with a His-tag for easy purification. PCSK9 is a key regulator of low-density lipoprotein receptor (LDLR) degradation, playing a crucial role in cholesterol metabolism. Inhibition of PCSK9 enhances LDLR recycling, reducing plasma LDL cholesterol levels. This recombinant mouse PCSK9 protein is widely used in cardiovascular disease research, particularly in studies on hypercholesterolemia and lipid metabolism. Its HEK293 expression system ensures proper post-translational modifications for optimal bioactivity in biochemical and pharmacological studies.
| Purity | ≥95% |
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