PD-1/PD-L1 Inhibitor 3

• CAT Number: I011726
• CAS Number: 1629654-95-0
• Molecular Formula: C89H126N24O18S
• Molecular Weight: 1852.17
• Purity: ≥95%
• Storage: 3 years-20°Cpowder
• SMILES: CCCCC1C(=O)NC(C(=O)NC(CSCC(=O)NC(C(=O)N(C(C(=O)NC(C(=O)N2CCCC2C(=O)NC(C(=O)NC(C(=O)N(CC(=O)NC(C(=O)NC(C(=O)NC(C(=O)N(C(C(=O)N1C)CCCC)C)CC3=CNC4=CC=CC=C43)CO)CC5=CNC6=CC=CC=C65)C)CC(C)C)CC7=CN=CN7)CC(=O)N)C)C)CC8=CC=CC=C8)C(=O)NCC(=O)N)CCCNC(=N)N

PD-1/PD-L1 Inhibitor 3（Programmed Death-1/Programmed Death-Ligand 1 Inhibitor 3）is a Macrocyclic inhibitor of PD-1/PD-L1 interaction with IC50 of 5.6 nM

Reference

[1] MILLER Michael Matthew, et al. Patent, Pub. No.:WO/2014/151634.