PD 122860

• CAT Number: I008587
• CAS Number: 122576-86-7
• Molecular Formula: C23H20F3N3O4S
• Molecular Weight: 491.48
• Purity: ≥95%
• Synonyms: PD122860; PD-122860; PD 122860;ethyl 5-cyano-6-methyl-2-((pyridin-4-ylsulfonyl)methyl)-4-(2-(trifluoromethyl)phenyl)-1,4-dihydropyridine-3-carboxylate
• Solubility: Soluble in DMSO
• Storage: 0 - 4 °C for short term, or -20 °C for long term
• IUPAC Name: ethyl 5-cyano-6-methyl-2-(pyridin-4-ylsulfonylmethyl)-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate
• InChI: InChI=1S/C23H20F3N3O4S/c1-3-33-22(30)21-19(13-34(31,32)15-8-10-28-11-9-15)29-14(2)17(12-27)20(21)16-6-4-5-7-18(16)23(24,25)26/h4-11,20,29H,3,13H2,1-2H3
• InChIKey: ZUAWKQNJMCYABQ-UHFFFAOYSA-N
• SMILES: CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2C(F)(F)F)C#N)C)CS(=O)(=O)C3=CC=NC=C3

PD 122860(CAT: I008587) is a novel dihydropyridine compound exhibiting dual activity as a sodium channel stimulator and calcium channel blocker. This unique pharmacological profile makes it a valuable tool for research into ion channel regulation, particularly in studies focused on cardiovascular function, neuronal signaling, and excitability disorders. By stimulating sodium channels and inhibiting calcium channels, PD 122860 offers insights into the intricate balance of ionic currents in cellular processes. Its high purity and consistency ensure reliable results, supporting investigations into potential therapeutic applications for cardiac arrhythmias, neuropathic pain, and other ion channel-related conditions.