For research use only. Not for therapeutic Use.
A potent D<sub>4</sub> dopamine receptor agonist (K<sub>i</sub> = 8.7 nM) with > 400-fold selectivity over D<sub>2</sub> and > 300-fold selectivity versus D<sub>3</sub> subtypes respectively. Induces synaptic translocation of CaMK II to postsynaptic sites in cultured prefrontal cortical neurons. Centrally active <em>in vivo</em>.
| Catalog Number | I010265 |
| CAS Number | 630117-19-0 |
| Synonyms | N-(Methyl-4-(2-cyanophenyl)piperazinyl-3-methylbenzamide maleate |
| Molecular Formula | C24H26N4O5 |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Solubility | Soluble to 100 mM in DMSO and to 25 mM in ethanol |
| Storage | Desiccate at -20C |
| IUPAC Name | (Z)-but-2-enedioic acid;N-[[4-(2-cyanophenyl)piperazin-1-yl]methyl]-3-methylbenzamide |
| InChI | InChI=1S/C20H22N4O.C4H4O4/c1-16-5-4-7-17(13-16)20(25)22-15-23-9-11-24(12-10-23)19-8-3-2-6-18(19)14-21;5-3(6)1-2-4(7)8/h2-8,13H,9-12,15H2,1H3,(H,22,25);1-2H,(H,5,6)(H,7,8)/b;2-1- |
| InChIKey | NAEUGRPISCANHO-BTJKTKAUSA-N |
| SMILES | CC1=CC=CC(=C1)C(=O)NCN2CCN(CC2)C3=CC=CC=C3C#N.C(=CC(=O)O)C(=O)O |
