PD-1/PD-L1 Inhibitor 2

• CAT Number: I002190
• CAS Number: 1675203-84-5
• Molecular Formula: C₂₅H₂₉N₃O₃
• Molecular Weight: 419.52
• Purity: ≥95%
• Synonyms: N-(2-(((2-methoxy-6-((2-methyl-[1,1/’-biphenyl]-3-yl)methoxy)pyridin-3-yl)methyl)amino)ethyl)acetamide
• Target: PD-1/PD-L1 interaction
• Solubility: DMSO: ≥ 30 mg/mL
• Storage: Store at -20°C
• IUPAC Name: N-[2-[[2-methoxy-6-[(2-methyl-3-phenylphenyl)methoxy]pyridin-3-yl]methylamino]ethyl]acetamide
• InChI: InChI=1S/C25H29N3O3/c1-18-22(10-7-11-23(18)20-8-5-4-6-9-20)17-31-24-13-12-21(25(28-24)30-3)16-26-14-15-27-19(2)29/h4-13,26H,14-17H2,1-3H3,(H,27,29)
• InChIKey: JEDPSOYOYVELLZ-UHFFFAOYSA-N
• SMILES: CC1=C(C=CC=C1C2=CC=CC=C2)COC3=NC(=C(C=C3)CNCCNC(=O)C)OC

PD-1/PD-L1 Inhibitor 2 (Cat No.:I002190) is a compound used in cancer immunotherapy. It is designed to inhibit the interaction between the PD-1 receptor on immune cells and the PD-L1 ligand on tumor cells. By blocking this interaction, it helps to boost the immune response against cancer.

Reference

[1]. Louis S. Chupak, et al. Compounds useful as immunomodulators. WO