PD123319

• CAT Number: I001172
• CAS Number: 130663-39-7
• Molecular Formula: C31H32N4O3
• Molecular Weight: 508.61
• Purity: ≥95%
• Storage: 3 years-20°Cpowder
• SMILES: CC1=C(C=CC(=C1)CN2C=NC3=C2CC(N(C3)C(=O)C(C4=CC=CC=C4)C5=CC=CC=C5)C(=O)O)N(C)C

PD 123319 is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of 34 nM.

Reference

[1] Blankley CJ, et al. J Med Chem, 1991, 34(11), 3248-3260.
[2] Boulay G, et al. Mol Pharmacol, 1992, 41(4), 809-815.
[3] Estrup TM, et al. J Renin Angiotensin Aldosterone Syst, 2001, 2(3), 188-192.
[4] Tamura M, et al. J Hypertens, 2000, 18(9), 1239-1246.