PDE10-IN-5

• CAT Number: I043443
• CAS Number: 898562-99-7
• Molecular Formula: C26H19F3N4O
• Molecular Weight: 460.45
• Purity: ≥95%
• Synonyms: 2-[[4-[4-pyridin-4-yl-2-(2,2,2-trifluoroethyl)pyrazol-3-yl]phenoxy]methyl]quinoline
• InChI: InChI=1S/C26H19F3N4O/c27-26(28,29)17-33-25(23(15-31-33)18-11-13-30-14-12-18)20-6-9-22(10-7-20)34-16-21-8-5-19-3-1-2-4-24(19)32-21/h1-15H,16-17H2
• InChIKey: KOQAWTNMUMMWMO-UHFFFAOYSA-N
• SMILES: C1=CC=C2C(=C1)C=CC(=N2)COC3=CC=C(C=C3)C4=C(C=NN4CC(F)(F)F)C5=CC=NC=C5

PDE10-IN-5 is a phosphodiesterase 10 (PDE 10) inhibitor, can be used for researching certain central nervous system (CNS) disorders[1].

Reference

[1]. Patrick Robert Verhoest, et al. Heteroaromatic quinoline compounds and their use as pde10 inhibitors. WO2006072828 A2 (Example 8)