For research use only. Not for therapeutic Use.
PDMP hydrochloride is a glucosylceramide synthase (GCS) inhibitor. PDMP hydrochloride induces apoptosis in K562/A02 cells. PDMP hydrochloride can be used in cancer (such as leukemia) research[1][2].
| Catalog Number | R067327 |
| CAS Number | 73257-80-4 |
| Molecular Formula | C23H39ClN2O3 |
| Purity | ≥95% |
| Reference | [1]. Casson L, et al. Inhibition of ceramide metabolism sensitizes human leukemia cells to inhibition of BCL2-like proteins. PLoS One. 2013;8(1):e54525. [2]. Yin L, et al. Effect of PDMP, a glucosylceramide synthase inhibitor, on reversion of daunorubicin resistance in human leukemia cell line K562/A02. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2010 Feb;18(1):79-84. |
