For research use only. Not for therapeutic Use.
PDMP hydrochloride(CAT: R067327) (1-phenyl-2-decanoylamino-3-morpholino-1-propanol hydrochloride) is a potent and selective inhibitor of glucosylceramide synthase, an essential enzyme in glycosphingolipid biosynthesis. By blocking this pathway, PDMP hydrochloride is widely used in studies of lipid metabolism, signal transduction, and lysosomal storage disorders such as Gaucher and Fabry diseases. It also serves as a valuable tool for investigating the role of glycosphingolipids in cancer, neurodegenerative diseases, and immune regulation. Supplied as a stable hydrochloride salt, PDMP is ideal for in vitro applications. Its ability to modulate sphingolipid pathways makes it indispensable in metabolic and cellular biology research.
| CAS Number | 80938-69-8 |
| Molecular Formula | C23H39ClN2O3 |
| Purity | ≥95% |
| IUPAC Name | N-(1-hydroxy-3-morpholin-4-yl-1-phenylpropan-2-yl)decanamide;hydrochloride |
| InChI | InChI=1S/C23H38N2O3.ClH/c1-2-3-4-5-6-7-11-14-22(26)24-21(19-25-15-17-28-18-16-25)23(27)20-12-9-8-10-13-20;/h8-10,12-13,21,23,27H,2-7,11,14-19H2,1H3,(H,24,26);1H |
| InChIKey | HVJHJOYQTSEKPK-UHFFFAOYSA-N |
| SMILES | CCCCCCCCCC(=O)NC(CN1CCOCC1)C(C2=CC=CC=C2)O.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
