PEAQX tetrasodium hydrate

• CAT Number: I005823
• CAS Number: 459836-30-7 (free base)
• Molecular Formula: C17H15BrN3Na4O6P
• Molecular Weight: 560.15
• Purity: ≥95%
• Synonyms: NVP-AAM077 tetrasodium hydrate, [[[(1S)-1-(4-Bromophenyl)ethyl]amino](1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl] phosphonic acid tetrasodium hydrate
• Target: Neuronal Signaling
• Solubility: DMSO: soluble10 mg/mL, clear
• Storage: Store at -20°C
• IC50: 270 nM
• IUPAC Name: tetrasodium;5-[[[(1S)-1-(4-bromophenyl)ethyl]amino]-phosphonatomethyl]quinoxaline-2,3-diolate;hydrate
• InChI: InChI=1S/C17H17BrN3O5P.4Na.H2O/c1-9(10-5-7-11(18)8-6-10)19-17(27(24,25)26)12-3-2-4-13-14(12)21-16(23)15(22)20-13;;;;;/h2-9,17,19H,1H3,(H,20,22)(H,21,23)(H2,24,25,26);;;;;1H2/q;4*+1;/p-4/t9-,17?;;;;;/m0...../s1
• InChIKey: SMGAGBKXHAHCGQ-VSYRWHDMSA-J
• SMILES: C[C@@H](C1=CC=C(C=C1)Br)NC(C2=C3C(=CC=C2)N=C(C(=N3)[O-])[O-])P(=O)([O-])[O-].O.[Na+].[Na+].[Na+].[Na+]

PEAQX tetrasodium hydrate（Cat No.:I005823）is a chemical compound used primarily in scientific research, particularly in studies related to ion channel modulation and neurotransmitter receptor activity. It is a potent and selective antagonist of the AMPA receptor, a subtype of glutamate receptors involved in excitatory neurotransmission in the brain. By blocking AMPA receptor activity, PEAQX tetrasodium hydrate helps to investigate the role of glutamatergic signaling in various neurological processes, including learning, memory, and neurodegenerative diseases. Further research into its potential applications in treating conditions like epilepsy and Alzheimer’s disease is ongoing.