For research use only. Not for therapeutic Use.
Pefcalcitol is a synthetic analog of vitamin D primarily used to treat psoriasis, a chronic skin condition characterized by red, scaly patches. It works by regulating the growth and development of skin cells, helping to reduce the thickening and scaling of the skin associated with psoriasis. Pefcalcitol is believed to exert its effects through interaction with vitamin D receptors in the skin cells, although the exact mechanism is not fully understood. It is typically applied topically and has shown effectiveness in improving psoriasis symptoms in clinical trials, offering a valuable treatment option for this condition.
| Catalog Number | I048024 |
| CAS Number | 381212-03-9 |
| Synonyms | M518101 |
| Molecular Formula | C26H34F5NO4 |
| Purity | 98% |
| Target | CFTR |
| Target Protein | SVCSMAZYWOQCBW-NVJMFHFGSA-N |
| Appearance | Solid |
| IUPAC Name | 2-[(1S)-1-[(3aS,4E,7aS)-4-[(2Z)-2-[(3S,5R)-3,5-dihydroxy-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-3a,5,6,7-tetrahydro-3H-inden-1-yl]ethoxy]-N-(2,2,3,3,3-pentafluoropropyl)acetamide |
| InChI | InChI=1S/C26H34F5NO4/c1-15-18(11-19(33)12-22(15)34)7-6-17-5-4-10-24(3)20(8-9-21(17)24)16(2)36-13-23(35)32-14-25(27,28)26(29,30)31/h6-8,16,19,21-22,33-34H,1,4-5,9-14H2,2-3H3,(H,32,35)/b17-6+,18-7-/t16-,19+,21-,22-,24+/m0/s1 |
| InChIKey | SVCSMAZYWOQCBW-NVJMFHFGSA-N |
| SMILES | CC(C1=CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C)OCC(=O)NCC(C(F)(F)F)(F)F |
