PEG-bis-amine (MW 8000)

• CAT Number: I040738
• CAS Number: 24991-53-5
• Molecular Formula: (C2H4O)nC4H12N2O
• Molecular Weight: 8000(Average)
• Purity: ≥95%

PEG-bis-amine (MW 8000) synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).

Reference

[1]. Han X, et al. 9-NC-loaded folate-conjugated polymer micelles as tumor targeted drug delivery system: preparation and evaluation in vitro. Int J Pharm. 2009 May 8;372(1-2):125-31.
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