For research use only. Not for therapeutic Use.
3,6-Dioxasuberic acid（Cat No.:I014555）, also known as ethylenedioxydiacetic acid (EDDA), is a carboxylic acid ligand that finds utility in various chemical and biochemical applications. As a carboxylic acid derivative, it can coordinate with metal ions, forming complexes that exhibit unique properties and reactivity. EDDA complexes have been employed in catalysis, metal extraction, and as chelating agents in chemical analysis and pharmaceutical applications. The methylenedioxy functionality in EDDA imparts flexibility to the ligand, allowing it to effectively coordinate with different metal centers and contribute to the stability and selectivity of the resulting complexes.
| Catalog Number | I014555 |
| CAS Number | 23243-68-7 |
| Synonyms | PEG2-(CH2CO2H)2;2,2′-(ethane-1,2-diylbis(oxy))diacetic acid |
| Molecular Formula | C6H10O6 |
| Purity | ≥95% |
| Target | PROTAC Linkers |
| Solubility | Soluble in DMSO |
| Storage | Room Temperature |
| IUPAC Name | 2-[2-(carboxymethoxy)ethoxy]acetic acid |
| InChI | InChI=1S/C6H10O6/c7-5(8)3-11-1-2-12-4-6(9)10/h1-4H2,(H,7,8)(H,9,10) |
| InChIKey | CQWXKASOCUAEOW-UHFFFAOYSA-N |
| SMILES | C(COCC(=O)O)OCC(=O)O |
| Reference | </br>1: Bonache MA, Alaimo A, Malo C, Millet O, Villarroel A, González-Muñiz R. Clicked bis-PEG-peptide conjugates for studying calmodulin-Kv7.2 channel binding. Org Biomol Chem. 2014 Nov 28;12(44):8877-87. doi: 10.1039/c4ob01338g. PubMed PMID: 25264745.</br>2: Aroua S, Schweizer WB, Yamakoshi Y. C60 pyrrolidine bis-carboxylic acid derivative as a versatile precursor for biocompatible fullerenes. Org Lett. 2014 Mar 21;16(6):1688-91. doi: 10.1021/ol500363r. Epub 2014 Mar 7. PubMed PMID: 24606113.</br>3: Kakkar D, Tiwari AK, Chuttani K, Khanna A, Datta A, Singh H, Mishra AK. Design, synthesis, and antimycobacterial property of PEG-bis(INH) conjugates. Chem Biol Drug Des. 2012 Aug;80(2):245-53. doi: 10.1111/j.1747-0285.2012.01394.x. Epub 2012 May 30. PubMed PMID: 22515497.</br></br> |
