For research use only. Not for therapeutic Use.
PEG3-C4-OBn is a polyethylene glycol (PEG)-based PROTAC linker. PEG3-C4-OBn can be used in the synthesis of the PROTAC SGK3 degrader-1 (HY-125878). PROTAC SGK3 degrader-1 is a potent SKG3 degrader based on PROTAC[1][2].
| Catalog Number | I017544 |
| CAS Number | 2381196-79-6 |
| Synonyms | 2-[2-(6-phenylmethoxyhexoxy)ethoxy]ethanol |
| Molecular Formula | C17H28O4 |
| Purity | ≥95% |
| InChI | InChI=1S/C17H28O4/c18-10-13-20-15-14-19-11-6-1-2-7-12-21-16-17-8-4-3-5-9-17/h3-5,8-9,18H,1-2,6-7,10-16H2 |
| InChIKey | BVCUBCXUEWSFBX-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)COCCCCCCOCCOCCO |
| Reference | [1]. Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader. ACS Chem Biol. 2019 Sep 5. [2]. Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader. ACS Chem Biol. 2019 Sep 20;14(9):2024-2034. |
