For research use only. Not for therapeutic Use.
PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
| Catalog Number | I044717 |
| CAS Number | 67439-82-1 |
| Synonyms | 2-[3-(2-hydroxyethoxy)propoxy]ethanol |
| Molecular Formula | C7H16O4 |
| Purity | ≥95% |
| InChI | InChI=1S/C7H16O4/c8-2-6-10-4-1-5-11-7-3-9/h8-9H,1-7H2 |
| InChIKey | KXSKAZFMTGADIV-UHFFFAOYSA-N |
| SMILES | C(COCCO)COCCO |
| Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
