Pelretin

• CAT Number: I034362
• CAS Number: 91587-01-8
• Molecular Formula: C23H28O2
• Molecular Weight: 336.47
• Purity: 98%
• Synonyms: Pelretin
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).
• IUPAC Name: 4-((1E,3E,5E)-4-methyl-6-(2,6,6-trimethylcyclohex-1-en-1-yl)hexa-1,3,5-trien-1-yl)benzoic acid
• InChI: InChI=1S/C23H28O2/c1-17(10-15-21-18(2)8-6-16-23(21,3)4)7-5-9-19-11-13-20(14-12-19)22(24)25/h5,7,9-15H,6,8,16H2,1-4H3,(H,24,25)/b9-5+,15-10+,17-7+
• InChIKey: YRNAHKPMDMVFMV-GMICYETFSA-N
• SMILES: O=C(O)C1=CC=C(/C=C/C=C(C)/C=C/C2=C(C)CCCC2(C)C)C=C1

Pelretin(CAT: I034362) is a synthetic retinoid that acts as an agonist of retinoic acid receptors (RARs), modulating gene expression involved in cell differentiation, proliferation, and apoptosis. Its mechanism is highly relevant in the oncology field, where it is utilized in research to explore therapies for cancers like acute promyelocytic leukemia and skin malignancies. Pelretin is also valuable for studying retinoid signaling pathways and their roles in epithelial cell regulation. Its specificity and activity make it a crucial compound for advancing research into retinoid-based therapeutic approaches and the development of novel anticancer strategies.