Penfluridol

• CAT Number: A000558
• CAS Number: 26864-56-2
• Molecular Formula: C28H27ClF5NO
• Molecular Weight: 523.97
• Purity: ≥95%
• Synonyms: 26864-56-2; 1-(4,4-bis(4-fluorophenyl)butyl)-4-(4-chloro-3-(trifluoromethyl)phenyl)piperidin-4-ol; Semap; TLP-607; McN-JR-16,341
• Target: Neuronal Signaling
• Storage: store at -20 ℃
• IUPAC Name: 1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]piperidin-4-ol
• InChI: 1S/C28H27ClF5NO/c29-26-12-7-21(18-25(26)28(32,33)34)27(36)13-16-35(17-14-27)15-1-2-24(19-3-8-22(30)9-4-19)20-5-10-23(31)11-6-20/h3-12,18,24,36H,1-2,13-17H2
• InChIKey: MDLAAYDRRZXJIF-UHFFFAOYSA-N
• SMILES: C1CN(CCC1(C2=CC(=C(C=C2)Cl)C(F)(F)F)O)CCCC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F

Penfluridol is a long-acting antipsychotic medication primarily used in the treatment of schizophrenia. It belongs to the fluphenazine-like class of drugs, which work by blocking dopamine receptors in the brain, particularly the D2 receptors, to help control symptoms such as hallucinations, delusions, and agitation. Penfluridol has a longer duration of action compared to other antipsychotics, requiring less frequent dosing. It may cause side effects like sedation, weight gain, and extrapyramidal symptoms, but is effective in managing chronic psychotic disorders.