For research use only. Not for therapeutic Use.
Penicillin G（Cat No.:R001177）, also known as benzylpenicillin, is a natural β-lactam antibiotic widely used to treat bacterial infections caused by Gram-positive organisms. It inhibits bacterial cell wall synthesis by targeting penicillin-binding proteins (PBPs), leading to cell lysis. Penicillin G is effective against streptococcal, staphylococcal, and some anaerobic infections. Administered via injection due to poor oral stability, it is commonly used for severe infections, including endocarditis, syphilis, and meningitis. Its historical significance and continued use underscore its importance in modern medicine and infectious disease treatment.
| Catalog Number | R001177 |
| CAS Number | 61-33-6 |
| Molecular Formula | C16H18N2O4S |
| Purity | ≥95% |
| Target | Antibiotic |
| Storage | -20°C |
| IUPAC Name | (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| InChI | InChI=1S/C16H18N2O4S/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22)/t11-,12+,14-/m1/s1 |
| InChIKey | JGSARLDLIJGVTE-MBNYWOFBSA-N |
| SMILES | CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)CC3=CC=CC=C3)C(=O)O)C |
| Reference | <p>Guzmán, Flavio, MD. /Beta Lactams Antibiotics (penicillins and Cephalosporins) Mechanism of Action.” <em>Medical Pharmacology</em>. Pharmacology Corner, 29 Nov. 2008. Web. 21 Aug. 2012.</p><p>Pitout JD, Sanders CC, Sanders WE Jr. Antimicrobial resistance with focus on beta-lactam resistance in gram-negative bacilli. Am J Med 1997; 103:51.</p></span></p> |
