For research use only. Not for therapeutic Use.
Pennogenin is a bioactive component which can be isolated from T. govanianum rhizomes. Pennogenin exhibits significant in vitro inhibitory effect on release of ROS[1].
Pennogenin exhibits significant level of oxidative burst suppressive activity[1].
Pennogenin exhibits significant in vitro inhibitory effect on release of ROS from whole blood, with an IC50 of 5.0 µg/mL[1].
| Catalog Number | I044862 |
| CAS Number | 507-89-1 |
| Synonyms | (1R,2S,4S,5’R,6R,7S,8S,9S,12S,13R,16S)-5′,7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2′-oxane]-8,16-diol |
| Molecular Formula | C27H42O4 |
| Purity | ≥95% |
| InChI | InChI=1S/C27H42O4/c1-16-7-12-26(30-15-16)17(2)27(29)23(31-26)14-22-20-6-5-18-13-19(28)8-10-24(18,3)21(20)9-11-25(22,27)4/h5,16-17,19-23,28-29H,6-15H2,1-4H3/t16-,17-,19+,20-,21+,22+,23+,24+,25+,26-,27-/m1/s1 |
| InChIKey | SYYHBUHOUUETMI-WJOMMTHPSA-N |
| SMILES | CC1CCC2(C(C3(C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)O)C)C)O)C)OC1 |
| Reference | [1]. Shafiq Ur Rahman, et al. Beneficial Effects of Trillium govanianum Rhizomes in Pain and Inflammation. Molecules. 2016 Aug; 21(8): 1095. |
