Pentamidine-d4 dihydrochloride

For research use only. Not for therapeutic Use.

  • CAT Number: S000234
  • CAS Number: 1276197-32-0
  • Molecular Formula: C19H22D4Cl2N4O2
  • Molecular Weight: 417.37
  • Purity: ≥95%
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Pentamidine-d4 dihydrochloride (CAS: 1276197-32-0), a premium pharmaceutical research compound designed for advanced antimicrobial and antiparasitic studies. As a deuterated analog of Pentamidine, it offers enhanced stability and improved pharmacokinetic properties. Pentamidine-d4 dihydrochloride is ideal for use in pharmacological and biochemical research, providing precise and reliable data for your studies. This high-purity compound ensures consistent results, aiding in the development of novel therapies for infections and parasitic diseases. Trusted by leading laboratories, Pentamidine-d4 dihydrochloride is your go-to solution for cutting-edge antimicrobial research. Unlock new possibilities in infection and parasite treatment with Pentamidine-d4 dihydrochloride, where innovation meets reliability.


Catalog Number S000234
CAS Number 1276197-32-0
Molecular Formula C19H22D4Cl2N4O2
Purity ≥95%
IUPAC Name 4-[5-(4-carbamimidoylphenoxy)-1,1,5,5-tetradeuteriopentoxy]benzenecarboximidamide;dihydrochloride
InChI InChI=1S/C19H24N4O2.2ClH/c20-18(21)14-4-8-16(9-5-14)24-12-2-1-3-13-25-17-10-6-15(7-11-17)19(22)23;;/h4-11H,1-3,12-13H2,(H3,20,21)(H3,22,23);2*1H/i12D2,13D2;;
InChIKey HWURPQUPKQFGJI-XQZXWLSLSA-N
SMILES [2H]C([2H])(CCCC([2H])([2H])OC1=CC=C(C=C1)C(=N)N)OC2=CC=C(C=C2)C(=N)N.Cl.Cl
Reference

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
[Content Brief]

[2]. Pathak MK, et al. Pentamidine is an inhibitor of PRL phosphatases with anticancer activity. Mol Cancer Ther. 2002 Dec;1(14):1255-64.
[Content Brief]

[3]. Nguewa, P.A., et al., Pentamidine is an antiparasitic and apoptotic drug that selectively modifies ubiquitin. Chem Biodivers, 2005. 2(10): p. 1387-400.
[Content Brief]

[4]. Sands M, et al. Pentamidine: a review. Rev Infect Dis. 1985 Sep-Oct;7(5):625-34.
[Content Brief]

[5]. David C. Bean, et al. Pentamidine: a drug to consider re-purposing in the targeted treatment of multi-drug resistant bacterial infections? J Lab Precis Med 2017;2:49.

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