For research use only. Not for therapeutic Use.
Pentamidine-d4 dihydrochloride (CAS: 1276197-32-0), a premium pharmaceutical research compound designed for advanced antimicrobial and antiparasitic studies. As a deuterated analog of Pentamidine, it offers enhanced stability and improved pharmacokinetic properties. Pentamidine-d4 dihydrochloride is ideal for use in pharmacological and biochemical research, providing precise and reliable data for your studies. This high-purity compound ensures consistent results, aiding in the development of novel therapies for infections and parasitic diseases. Trusted by leading laboratories, Pentamidine-d4 dihydrochloride is your go-to solution for cutting-edge antimicrobial research. Unlock new possibilities in infection and parasite treatment with Pentamidine-d4 dihydrochloride, where innovation meets reliability.
Catalog Number | S000234 |
CAS Number | 1276197-32-0 |
Molecular Formula | C19H22D4Cl2N4O2 |
Purity | ≥95% |
IUPAC Name | 4-[5-(4-carbamimidoylphenoxy)-1,1,5,5-tetradeuteriopentoxy]benzenecarboximidamide;dihydrochloride |
InChI | InChI=1S/C19H24N4O2.2ClH/c20-18(21)14-4-8-16(9-5-14)24-12-2-1-3-13-25-17-10-6-15(7-11-17)19(22)23;;/h4-11H,1-3,12-13H2,(H3,20,21)(H3,22,23);2*1H/i12D2,13D2;; |
InChIKey | HWURPQUPKQFGJI-XQZXWLSLSA-N |
SMILES | [2H]C([2H])(CCCC([2H])([2H])OC1=CC=C(C=C1)C(=N)N)OC2=CC=C(C=C2)C(=N)N.Cl.Cl |
Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Pathak MK, et al. Pentamidine is an inhibitor of PRL phosphatases with anticancer activity. Mol Cancer Ther. 2002 Dec;1(14):1255-64. [3]. Nguewa, P.A., et al., Pentamidine is an antiparasitic and apoptotic drug that selectively modifies ubiquitin. Chem Biodivers, 2005. 2(10): p. 1387-400. [4]. Sands M, et al. Pentamidine: a review. Rev Infect Dis. 1985 Sep-Oct;7(5):625-34. [5]. David C. Bean, et al. Pentamidine: a drug to consider re-purposing in the targeted treatment of multi-drug resistant bacterial infections? J Lab Precis Med 2017;2:49. |