Pentamidine Isethionate

• CAT Number: A000242
• CAS Number: 140-64-7
• Molecular Formula: C23H36N4O10S2
• Molecular Weight: 592.68
• Purity: ≥95%
• Synonyms: 140-64-7; Pentamidine isethionate salt; 4,4/’-(Pentane-1,5-diylbis(oxy))dibenzimidamide bis(2-hydroxyethanesulfonate); Pentamidine diisethionate; Pentacarinat
• Target: Metabolic Enzyme/Protease
• Solubility: >22.6mg/mL in DMSO
• Storage: Store at -20°C
• IUPAC Name: 4-[5-(4-carbamimidoylphenoxy)pentoxy]benzenecarboximidamide;2-hydroxyethanesulfonic acid
• InChI: InChI=1S/C19H24N4O2.2C2H6O4S/c20-18(21)14-4-8-16(9-5-14)24-12-2-1-3-13-25-17-10-6-15(7-11-17)19(22)23;2*3-1-2-7(4,5)6/h4-11H,1-3,12-13H2,(H3,20,21)(H3,22,23);2*3H,1-2H2,(H,4,5,6)
• InChIKey: YBVNFKZSMZGRAD-UHFFFAOYSA-N
• SMILES: C1=CC(=CC=C1C(=N)N)OCCCCCOC2=CC=C(C=C2)C(=N)N.C(CS(=O)(=O)O)O.C(CS(=O)(=O)O)O

Pentamidine Isethionate（Cat No.:A000242）is an antiprotozoal and antifungal agent primarily used to treat infections like Pneumocystis jirovecii pneumonia (PCP), African trypanosomiasis, and leishmaniasis. It works by interfering with nucleic acid and protein synthesis in susceptible organisms, disrupting their cellular functions. Administered via injection or inhalation, it is particularly effective in immunocompromised patients, such as those with HIV/AIDS. Pentamidine isethionate’s broad-spectrum activity and efficacy make it a critical option for managing opportunistic infections. Its use requires careful monitoring due to potential side effects like renal and cardiac toxicity.

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