Pentolinium Tartrate

• CAT Number: I008635
• CAS Number: 52-62-0
• Molecular Formula: C23H42N2O12
• Molecular Weight: 538.59
• Purity: ≥95%
• Synonyms: Pentolinium Tartrate ; Pendine; Recuryl; Tensilest; Pentalinium tartrate; Pentolinium bitartrate; Tartrate, Pentolinium; Tartrate, Pentolonium;;1-methyl-1-[5-(1-methylpyrrolidin-1-ium-1-yl)pentyl]pyrrolidin-1-ium;(2R,3R)-2,3,4-trihydroxy-4-oxobutano
• Target: Nicotinic Antagonist
• Solubility: Soluble in DMSO, not in water
• Storage: -20°C

Pentolinium Tartrate is a ganglionic blocking agent that inhibits the transmission of nerve impulses in the autonomic nervous system. It works by blocking nicotinic acetylcholine receptors at the autonomic ganglia, leading to a reduction in sympathetic and parasympathetic nervous activity. Pentolinium tartrate was historically used to manage severe hypertension, particularly in cases of hypertensive crises, by inducing vasodilation and reducing blood pressure. However, its use has declined with the advent of more selective and safer antihypertensive agents. Pentolinium tartrate remains a valuable tool for research into autonomic nervous system function and blood pressure regulation.