For research use only. Not for therapeutic Use.
Pentosan Polysulfate Sodium(Cat No.:M097689)is a sulfated polysaccharide primarily used in the treatment of interstitial cystitis and bladder pain. It acts by binding to the bladder wall, enhancing the urothelial barrier function and reducing inflammation. This compound has also shown promise in managing osteoarthritis and various vascular conditions due to its anti-inflammatory and anticoagulant properties. With a mechanism involving the modulation of heparan sulfate, Pentosan Polysulfate Sodium is essential for research in inflammation, tissue repair, and drug delivery systems. It is available for laboratory and pharmaceutical applications.
Catalog Number | M097689 |
CAS Number | 140207-93-8 |
Purity | ≥95% |
Target | HIV |
Storage | -20°C |
IUPAC Name | decasodium;3-methoxy-6-[2-(6-methoxy-4,5-disulfonatooxyoxan-3-yl)oxy-5-[5-(5-methoxy-3,4-disulfonatooxyoxan-2-yl)oxy-3,4-disulfonatooxyoxan-2-yl]oxy-4-sulfonatooxyoxan-3-yl]oxy-4,5-disulfonatooxyoxane-2-carboxylate |
InChI | InChI=1S/C29H48O50S9.10Na/c1-59-8-4-63-27(21(77-86(50,51)52)12(8)71-80(32,33)34)68-11-7-65-28(22(78-87(53,54)55)15(11)74-83(41,42)43)67-9-6-64-26(66-10-5-62-25(61-3)20(76-85(47,48)49)14(10)73-82(38,39)40)19(13(9)72-81(35,36)37)70-29-23(79-88(56,57)58)17(75-84(44,45)46)16(60-2)18(69-29)24(30)31;;;;;;;;;;/h8-23,25-29H,4-7H2,1-3H3,(H,30,31)(H,32,33,34)(H,35,36,37)(H,38,39,40)(H,41,42,43)(H,44,45,46)(H,47,48,49)(H,50,51,52)(H,53,54,55)(H,56,57,58);;;;;;;;;;/q;10*+1/p-10 |
InChIKey | MSJQCBORNZDNDU-UHFFFAOYSA-D |
SMILES | COC1COC(C(C1OS(=O)(=O)[O-])OS(=O)(=O)[O-])OC2COC(C(C2OS(=O)(=O)[O-])OS(=O)(=O)[O-])OC3COC(C(C3OS(=O)(=O)[O-])OC4C(C(C(C(O4)C(=O)[O-])OC)OS(=O)(=O)[O-])OS(=O)(=O)[O-])OC5COC(C(C5OS(=O)(=O)[O-])OS(=O)(=O)[O-])OC.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+] |
Reference | [1]. Schuchman EH, et al. Pentosan polysulfate: a novel therapy for the mucopolysaccharidoses. PLoS One. 2013;8(1):e54459. |