Pepinh-TRIF TFA

For research use only. Not for therapeutic Use.

  • CAT Number: I044251
  • Molecular Formula: C180H279F3N58O40S2
  • Molecular Weight: 4016.63
  • Purity: ≥95%
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Pepinh-TRIF (TFA) is a 30 aa peptide that blocks TIR-domain-containing adapter-inducing interferon-β (TRIF) signaling by interfering with TLR-TRIF interaction[1].
Pepinh-TRIF (40 μM, 6 hours) blocks the expression and production of IL-33 stimulated by polyI:C or flagellin, and also greatly suppresses the stimulated IκB-α phosphorylation and degradation in HCECs[1].?
Pepinh-TRIF (40 μM, 6 hours) suppresses NF-κB activation with p65 protein nuclear translocation [1].


Catalog Number I044251
Molecular Formula C180H279F3N58O40S2
Purity ≥95%
Reference

[1]. Amal Hasan, et al. TNF-α in Combination with Palmitate Enhances IL-8 Production via The MyD88- Independent TLR4 Signaling Pathway: Potential Relevance to Metabolic Inflammation. Int J Mol Sci. 2019 Aug 23;20(17):4112.
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