Peroxy Orange 1

• CAT Number: I010682
• CAS Number: 1199576-10-7
• Molecular Formula: C32H32BNO5
• Molecular Weight: 521.42
• Purity: ≥95%
• Synonyms: Alternative Name: PO1
• Target: Fluorescent Probes
• Solubility: Soluble to 10 mM in DMSO
• Storage: Store at -20C
• IUPAC Name: 6'-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)spiro[2-benzofuran-3,10'-3-oxa-17-azapentacyclo[11.7.1.02,11.04,9.017,21]henicosa-1(21),2(11),4(9),5,7,12-hexaene]-1-one
• InChI: InChI=1S/C32H32BNO5/c1-30(2)31(3,4)39-33(38-30)20-13-14-24-26(18-20)36-28-22-11-8-16-34-15-7-9-19(27(22)34)17-25(28)32(24)23-12-6-5-10-21(23)29(35)37-32/h5-6,10,12-14,17-18H,7-9,11,15-16H2,1-4H3
• InChIKey: KNTNXZHHCPNNGB-UHFFFAOYSA-N
• SMILES: B1(OC(C(O1)(C)C)(C)C)C2=CC3=C(C=C2)C4(C5=CC=CC=C5C(=O)O4)C6=C(O3)C7=C8C(=C6)CCCN8CCC7

Peroxy Orange 1 (CAT: I010682) is a fluorescent probe specifically designed for the imaging of hydrogen peroxide (H2O2) in biological systems. It exhibits strong fluorescence upon reaction with H2O2, allowing for the visualization and quantification of H2O2 levels in cells and tissues. The probe utilizes a specific chemical reaction with H2O2 to generate a fluorescent signal, enabling researchers to monitor and study the dynamics of H2O2 in biological processes such as oxidative stress, inflammation, and cell signaling. The fluorescence properties of Peroxy Orange 1 make it a valuable tool for studying H2O2-related processes and exploring its role in various biological contexts.

Reference

1.Dickinson, Bryan C., Calvin Huynh, and Christopher J. Chang. "A palette of fluorescent probes with varying emission colors for imaging hydrogen peroxide signaling in living cells." Journal of the American Chemical Society 132.16 (2010): 5906-5915.
2.Oliveira-Marques, Virginia, et al. "Role of hydrogen peroxide in NF-κB activation: from inducer to modulator." Antioxidants & redox signaling 11.9 (2009): 2223-2243.