Pertussis Toxin

• CAT Number: I010699
• CAS Number: 70323-44-3
• Purity: ≥95%
• Storage: Store at +4C

Pertussis toxin (Cat No.:I010699) is a protein exotoxin produced by the bacterium Bordetella pertussis, the causative agent of whooping cough (pertussis). PTX acts by interfering with G-protein-coupled receptor (GPCR) signaling, inhibiting the normal function of the G-proteins that regulate cellular processes. This disruption leads to immune system suppression and altered cellular responses, contributing to the pathogenesis of whooping cough. In addition to its role in disease, PTX is used in research to study cellular signaling pathways and as an adjuvant in vaccine development, enhancing immune responses to other antigens.