For research use only. Not for therapeutic Use.
Pexopiprant is an oral antagonist of the prostaglandin D2 receptor 2 (DP2),Ki ＜ 100nM. Pexopiprant can be used in studies of asthma[1].
| Catalog Number | I034460 |
| CAS Number | 932708-14-0 |
| Synonyms | 2-[8-chloro-3-[(4-chlorophenyl)methyl]-4-(difluoromethoxy)-2-ethylquinolin-5-yl]oxyacetic acid |
| Molecular Formula | C21H17Cl2F2NO4 |
| Purity | ≥95% |
| InChI | InChI=1S/C21H17Cl2F2NO4/c1-2-15-13(9-11-3-5-12(22)6-4-11)20(30-21(24)25)18-16(29-10-17(27)28)8-7-14(23)19(18)26-15/h3-8,21H,2,9-10H2,1H3,(H,27,28) |
| InChIKey | LZLJEKKWOIJMSR-UHFFFAOYSA-N |
| SMILES | CCC1=NC2=C(C=CC(=C2C(=C1CC3=CC=C(C=C3)Cl)OC(F)F)OCC(=O)O)Cl |
| Reference | [1]. Cramp, Michael Colin; Arienzo, Rosa; Hynd, George; Crackett, Peter; Griffon, Yann; Harrison, Trevor Keith; Ray, Nicholas Charles; Finch, Harry; Montana, John Gary.Preparation of quinoline derivatives as CRTH2 antagonists. WO2007036743 A2. |
