For research use only. Not for therapeutic Use.
PF 04531083 is a selective NaV1.8 blocker, and used for the research of neuropathic/inflammatory pain.
Catalog Number | I020128 |
CAS Number | 1079400-07-9 |
Synonyms | N-[6-amino-5-(2-chloro-5-methoxyphenyl)pyridin-2-yl]-2-methylpyrazole-3-carboxamide |
Molecular Formula | C17H16ClN5O2 |
Purity | ≥95% |
InChI | InChI=1S/C17H16ClN5O2/c1-23-14(7-8-20-23)17(24)22-15-6-4-11(16(19)21-15)12-9-10(25-2)3-5-13(12)18/h3-9H,1-2H3,(H3,19,21,22,24) |
InChIKey | ZRJGMDIPCQOGNI-UHFFFAOYSA-N |
SMILES | CN1C(=CC=N1)C(=O)NC2=NC(=C(C=C2)C3=C(C=CC(=C3)OC)Cl)N |
Reference | [1]. Bagal SK, et al. Recent progress in sodium channel modulators for pain. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3690-9. |