PF 04531083

For research use only. Not for therapeutic Use.

  • CAT Number: I020128
  • CAS Number: 1079400-07-9
  • Molecular Formula: C17H16ClN5O2
  • Molecular Weight: 357.79
  • Purity: ≥95%
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PF 04531083 is a selective NaV1.8 blocker, and used for the research of neuropathic/inflammatory pain.


Catalog Number I020128
CAS Number 1079400-07-9
Synonyms

N-[6-amino-5-(2-chloro-5-methoxyphenyl)pyridin-2-yl]-2-methylpyrazole-3-carboxamide

Molecular Formula C17H16ClN5O2
Purity ≥95%
InChI InChI=1S/C17H16ClN5O2/c1-23-14(7-8-20-23)17(24)22-15-6-4-11(16(19)21-15)12-9-10(25-2)3-5-13(12)18/h3-9H,1-2H3,(H3,19,21,22,24)
InChIKey ZRJGMDIPCQOGNI-UHFFFAOYSA-N
SMILES CN1C(=CC=N1)C(=O)NC2=NC(=C(C=C2)C3=C(C=CC(=C3)OC)Cl)N
Reference

[1]. Bagal SK, et al. Recent progress in sodium channel modulators for pain. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3690-9.
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