For research use only. Not for therapeutic Use.
PF-05089771 (Cat No.:I000939) is an active metabolite of Roflumilast used in the treatment of chronic obstructive pulmonary disease (COPD). This compound inhibits the enzyme phosphodiesterase-4 (PDE-4), reducing inflammation and promoting bronchodilation. Administered orally, PF-05089771 exhibits anti-inflammatory properties and helps alleviate symptoms of COPD.
| Catalog Number | I000939 |
| CAS Number | 1235403-62-9 |
| Molecular Formula | C18H12Cl2FN5O3S2 |
| Purity | ≥95% |
| Target | Sodium Channel |
| Solubility | DMSO: ≥ 34 mg/mL |
| Storage | Store at -20°C |
| IUPAC Name | 4-[2-(5-amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-(1,3-thiazol-4-yl)benzenesulfonamide |
| InChI | InChI=1S/C18H12Cl2FN5O3S2/c19-9-1-2-14(10(3-9)11-6-24-25-18(11)22)29-15-5-13(21)16(4-12(15)20)31(27,28)26-17-7-30-8-23-17/h1-8,26H,(H3,22,24,25) |
| InChIKey | ZYSCOUXLBXGGIM-UHFFFAOYSA-N |
| SMILES | C1=CC(=C(C=C1Cl)C2=C(NN=C2)N)OC3=CC(=C(C=C3Cl)S(=O)(=O)NC4=CSC=N4)F |
