PF-06456384 trihydrochloride

• CAT Number: I034490
• CAS Number: 1834610-75-1
• Molecular Formula: C35H35Cl3F3N7O3S2
• Molecular Weight: 829.17
• Purity: 98%
• Synonyms: PF-06456384 trihydrochloride
• Target: Sodium Channel
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Store at -20°C
• IUPAC Name: 3-Cyano-4-[[3-[2-[[[2-(4-piperidinyl)ethyl]amino]methyl]-4-pyridinyl]-3′-(trifluoromethyl)[1,1′-biphenyl]-4-yl]oxy]-N-1,2,4-thiadiazol-5-yl-benzenesulfonamide trihydrochloride
• InChI: InChI=1S/C35H32F3N7O3S2.3ClH/c36-35(37,38)28-3-1-2-24(16-28)25-4-6-33(48-32-7-5-30(18-27(32)20-39)50(46,47)45-34-43-22-44-49-34)31(19-25)26-11-15-42-29(17-26)21-41-14-10-23-8-12-40-13-9-23;;;/h1-7,11,15-19,22-23,40-41H,8-10,12-14,21H2,(H,43,44,45);3*1H
• InChIKey: KUXFHGFSLKUFBC-UHFFFAOYSA-N
• SMILES: O=S(C1=CC=C(OC2=CC=C(C3=CC=CC(C(F)(F)F)=C3)C=C2C4=CC(CNCCC5CCNCC5)=NC=C4)C(C#N)=C1)(NC6=NC=NS6)=O.[H]Cl.[H]Cl.[H]Cl

PF-06456384（Cat No.:I034490） trihydrochloride is a small molecule inhibitor of spleen tyrosine kinase (SYK), a protein kinase that plays a key role in regulating immune responses and inflammation. It has a chemical structure that consists of a pyrazole and a propanamide moiety, with a fluorophenyl and a chloromethoxyphenyl group attached to the pyrazole.