For research use only. Not for therapeutic Use.
PF-07054894 is a potent CCR6 antagonist. PF-07054894 targets G protein-coupled receptor (GPCR). PF-07054894 can be used in research of inflammatory bowel disease[1].
Catalog Number | I042298 |
CAS Number | 2413693-96-4 |
Synonyms | 4-[[2-[[(R)-(1,4-dimethylpyrazol-3-yl)-(1-methylcyclopentyl)methyl]amino]-3,4-dioxocyclobuten-1-yl]amino]-3-hydroxy-N,N-dimethylpyridine-2-carboxamide |
Molecular Formula | C24H30N6O4 |
Purity | ≥95% |
InChI | InChI=1S/C24H30N6O4/c1-13-12-30(5)28-15(13)22(24(2)9-6-7-10-24)27-17-16(20(32)21(17)33)26-14-8-11-25-18(19(14)31)23(34)29(3)4/h8,11-12,22,27,31H,6-7,9-10H2,1-5H3,(H,25,26)/t22-/m0/s1 |
InChIKey | WZBSYWCLIMRAHO-QFIPXVFZSA-N |
SMILES | CC1=CN(N=C1C(C2(CCCC2)C)NC3=C(C(=O)C3=O)NC4=C(C(=NC=C4)C(=O)N(C)C)O)C |
Reference | [1]. Gómez S, et, al. Desarrollo de anticuerpos terapéuticos contra el receptor CCR6 humano. |