PF-07208254

• CAT Number: I040569
• CAS Number: 2573122-40-2
• Molecular Formula: C7H2ClFO2S2
• Molecular Weight: 236.67
• Purity: ≥95%
• Synonyms: 6-chloro-2-fluorothieno[3,2-b]thiophene-5-carboxylic acid
• InChI: InChI=1S/C7H2ClFO2S2/c8-4-5-2(1-3(9)13-5)12-6(4)7(10)11/h1H,(H,10,11)
• InChIKey: UXMBSHHPPVOPJU-UHFFFAOYSA-N
• SMILES: C1=C(SC2=C1SC(=C2Cl)C(=O)O)F

PF-07208254 is a potent inhibitor of BDK. PF-07208254 improves cardiometabolic endpoints in mice[1].

Reference

[1]. Roth Flach RJ, et al. Small molecule branched-chain ketoacid dehydrogenase kinase (BDK) inhibitors with opposing effects on BDK protein levels. Nat Commun. 2023 Aug 9;14(1):4812.
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