For research use only. Not for therapeutic Use.
PF 429242 is known as a S1P inhibitor with an IC50 of 170 nM, showing no significant inhibition of trypsin, elastase, proteinase K, plasmin, kallikren, factor XIa, thrombin, or furin at concentrations up to 100 μM and only modest inhibition of urokinase (IC50 = 50 μM) and factor Xa (IC50 = 100 μM).
| Catalog Number | I005885 |
| CAS Number | 947303-87-9 |
| Molecular Formula | C25H35N3O2 |
| Purity | ≥95% |
| Storage | 3 years -20°C powder |
| SMILES | CCN(CC)CC1=CC=C(C=C1)C(=O)N(CCC2=CC=CC=C2OC)C3CCNC3 |
| Reference | [1] Bruce A Hay, et al. Bioorg Med Chem Lett . 2007 Aug 15;17(16):4411-4. |
