For research use only. Not for therapeutic Use.
PF-5081090（Cat No.:R056247）is an experimental small-molecule drug under investigation for its potential to treat chronic pain. It selectively targets and inhibits the NLRP3 inflammasome, a key protein complex involved in the inflammatory response. By modulating this pathway, PF-5081090 aims to reduce inflammation and associated pain, particularly in conditions like osteoarthritis and other inflammatory disorders. Preclinical studies suggest it could provide a new approach to managing chronic pain, offering an alternative to traditional pain management therapies by targeting the underlying inflammatory mechanisms rather than just symptom relief.
| CAS Number | 1312473-63-4 |
| Synonyms | (2R)-4-[4-(2-fluoro-4-methoxyphenyl)-2-oxopyridin-1-yl]-N-hydroxy-2-methyl-2-methylsulfonylbutanamide |
| Molecular Formula | C18H21FN2O6S |
| Purity | ≥95% |
| IUPAC Name | (2R)-4-[4-(2-fluoro-4-methoxyphenyl)-2-oxopyridin-1-yl]-N-hydroxy-2-methyl-2-methylsulfonylbutanamide |
| InChI | InChI=1S/C18H21FN2O6S/c1-18(17(23)20-24,28(3,25)26)7-9-21-8-6-12(10-16(21)22)14-5-4-13(27-2)11-15(14)19/h4-6,8,10-11,24H,7,9H2,1-3H3,(H,20,23)/t18-/m1/s1 |
| InChIKey | DNVUWHWBCMGQLU-GOSISDBHSA-N |
| SMILES | C[C@@](CCN1C=CC(=CC1=O)C2=C(C=C(C=C2)OC)F)(C(=O)NO)S(=O)(=O)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
