PF-562271 HCl

• CAT Number: I008426
• CAS Number: 939791-41-0
• Molecular Formula: C21H21ClF3N7O3S
• Molecular Weight: 543.95
• Purity: ≥95%
• Storage: 3 years-20°Cpowder
• SMILES: CN(C1=C(C=CC=N1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)C4)S(=O)(=O)C.Cl

PF-562271 HCl is the hydrochloride salt of PF-562271, which is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs. Phase 1.

Reference

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