PF00835231

• CAT Number: I034464
• CAS Number: 870153-29-0
• Molecular Formula: C24H32N4O6
• Molecular Weight: 472.54
• Purity: 98%
• Synonyms: PF 00835231; PF-00835231; PF00835231; PF 835231; PF-835231; PF835231
• Target: SARS-CoV
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Store at -20°C
• IUPAC Name: N-[(2S)-1-[[(2S)-4-hydroxy-3-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide
• InChI: InChI=1S/C24H32N4O6/c1-13(2)9-18(23(32)27-17(20(30)12-29)10-14-7-8-25-22(14)31)28-24(33)19-11-15-16(26-19)5-4-6-21(15)34-3/h4-6,11,13-14,17-18,26,29H,7-10,12H2,1-3H3,(H,25,31)(H,27,32)(H,28,33)/t14-,17-,18-/m0/s1
• InChIKey: QDIMHKWNHMVDJB-WBAXXEDZSA-N
• SMILES: CC(C)C[C@@H](C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)CO)NC(=O)C2=CC3=C(N2)C=CC=C3OC

PF00835231（Cat No.:I034464）is a potent, selective inhibitor of the protein kinase CK1 (casein kinase 1), which plays a crucial role in various cellular processes, including the regulation of circadian rhythms, DNA damage response, and Wnt/β-catenin signaling pathways. By targeting CK1, PF00835231 is being investigated for its potential therapeutic applications in cancer, neurodegenerative diseases, and circadian rhythm disorders. It offers a valuable tool for studying the functional role of CK1 in cellular pathways and may contribute to the development of novel treatments for conditions related to CK1 dysregulation.

Reference

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