For research use only. Not for therapeutic Use.
PF9601N, an monoamine oxidase B (MAO-B) inhibitor, possesses neuroprotective properties in several in vitro and in vivo models of Parkinson’s disease (PD). PF9601N can be used for the research of neurodegenerative diseases mediated by excitotoxicity[1]. PF9601N is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
| Catalog Number | I012300 |
| CAS Number | 133845-63-3 |
| Synonyms | N-[(5-phenylmethoxy-1H-indol-2-yl)methyl]prop-2-yn-1-amine |
| Molecular Formula | C19H18N2O |
| Purity | ≥95% |
| InChI | InChI=1S/C19H18N2O/c1-2-10-20-13-17-11-16-12-18(8-9-19(16)21-17)22-14-15-6-4-3-5-7-15/h1,3-9,11-12,20-21H,10,13-14H2 |
| InChIKey | YFPNAYXYKXAKJC-UHFFFAOYSA-N |
| SMILES | C#CCNCC1=CC2=C(N1)C=CC(=C2)OCC3=CC=CC=C3 |
| Reference | [1]. Irene Bolea, et al. Neuroprotective effects of the MAO-B inhibitor, PF9601N, in an in vivo model of excitotoxicity. CNS Neurosci Ther. 2014 Jul;20(7):641-50. |
